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GLP-1 Semaglutide Injection

Medically-guided GLP-1 therapy that targets appetite regulation for sustainable weight loss

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Introduction

GLP-1 Semaglutide Injection for Weight Loss

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Crash diets and extreme exercise plans often fail because they work against your biology rather than with it.

GLP-1 semaglutide injection is a doctor-prescribed treatment used in medical weight loss programmes in Singapore, designed to target the hormonal and neurological pathways that drive hunger, cravings, and portion control.

As a GLP-1 receptor agonist, semaglutide works by mimicking glucagon-like peptide-1, a naturally occurring hormone involved in appetite regulation and metabolic control. This allows for reduced caloric intake, improved portion control, and gradual fat reduction under structured medical supervision.

How

GLP-1 Injection Works for Weight Loss

GLP-1 receptors are located in areas of the brain that regulate satiety and food intake. When a GLP-1 semaglutide injection is administered, it activates these receptors to enhance fullness signalling and reduce hunger cues.

As a GLP-1 receptor agonist, semaglutide injection works by:

  • Increasing feelings of fullness

  • Reducing hunger and food cravings

  • Slowing gastric emptying

  • Improving insulin response

  • Supporting steady, sustainable weight reduction

Through appetite regulation and metabolic modulation, GLP-1 injection therapy helps patients achieve structured weight loss within a medically supervised programme.

Clinical studies have shown that GLP-1 receptor agonists may support clinically meaningful weight reduction when used as part of a comprehensive medical weight management plan. Individual results vary, and treatment suitability must be assessed by a doctor.

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Who

Is Suitable for GLP-1 Semaglutide Injection

GLP-1 semaglutide injection may be considered for adults seeking doctor-supervised medical weight loss in Singapore.

In general, GLP-1 semaglutide injections may be appropriate for individuals who:

  • Have a Body Mass Index (BMI) of 23 or above based on Asian risk criteria

  • Have excess body weight associated with metabolic risk factors

  • Have experienced difficulty achieving sustained weight reduction through diet and exercise alone

  • Are medically suitable following clinical evaluation

In certain cases, individuals with a BMI slightly below the threshold may be considered if they have weight-related metabolic risk factors or other clinical indications.

GLP-1 injection is a prescription medication and suitability is determined on a case-by-case basis following medical evaluation by a doctor to ensure that the treatment is appropriate and safe.

What

To Expect During GLP-1 Semaglutide Treatment

Weekly Administration

GLP-1 semaglutide injections are administered once weekly as a subcutaneous injection, typically into the abdomen, thigh, or upper arm. The once-weekly injection helps maintain consistent appetite regulation and steady therapeutic levels.

During your first visit, a doctor will guide you on proper injection technique and the dosing schedule.

Dose Escalation and Monitoring

The treatment usually starts at a lower dose to help the body adjust and minimise potential side effects. The dose may be increased gradually over several weeks depending on tolerance, weight loss response, metabolic profile, and clinical goals.

Follow-Up Consultations

After starting GLP-1 semaglutide injection, patients typically have follow-up consultations with our doctors once a month. During these visits, our doctors monitor side effects and overall tolerance to ensure the treatment remains safe and manageable.

They will also assess weight loss progress and review metabolic markers to track effectiveness. If needed, the dosage may be adjusted based on individual response, tolerance, and treatment goals.

Each consultation provides an opportunity to review overall health and discuss next steps, ensuring that the therapy is tailored to each patient’s needs and supports sustainable weight reduction.

FAQ

Frequently Asked Questions

What happens if I stop GLP-1 semaglutide treatment?

If you stop GLP-1 therapy, the appetite-suppressing effects gradually decrease. Many patients choose to discontinue once they have reached their personal weight loss goals, using the healthy habits they developed during treatment to maintain progress.

This doesn’t mean your efforts are lost — it’s an opportunity to reinforce healthy habits you’ve built. This approach makes stopping treatment a positive milestone rather than a setback. Continuing lifestyle strategies such as balanced meals, portion control, and regular physical activity helps support sustainable, long-term weight management even after discontinuing the medication.

The key is to treat GLP-1 as a tool to jumpstart sustainable weight management, not a lifelong crutch.

Most patients find the injections very manageable. The injection is subcutaneous, usually into the abdomen, thigh, or upper arm, and is designed for comfort and ease of use.

Any mild discomfort is brief, and minor redness or swelling usually resolves quickly. With guidance from our doctors, most people feel confident self-administering their weekly injection at home, making it a simple and low-stress part of their routine.

GLP-1 semaglutide injections are a powerful tool for supporting weight loss, but it works best when combined with healthy lifestyle habits.

While it helps reduce hunger, improve portion control, and support steady weight reduction, it does not replace the benefits of a balanced diet and regular exercise. Patients who combine Wegovy with mindful eating, portion control, and physical activity tend to achieve more sustainable results, improve overall metabolic health, and maintain their weight loss long-term.

Think of it as a partner in your weight loss journey, it gives your body support while you build the habits that keep the weight off for good.

The most common side effects are generally gastrointestinal, including nausea, bloating, and mild diarrhea. These effects are often temporary and tend to decrease as the body adjusts to the medication. Regular follow-up consultations allow doctors to monitor side effects, adjust dosage if necessary, and ensure treatment safety.

Restylane® Kysse Lip Fillers
What is Restylane® Kysse

Dubbed as the gold standard of lip fillers, Restylane® Kysse is a hyaluronic acid (HA) filler that’s designed specifically for our lips. Using XpresHAn™ Technology, it provides flexible movement and natural-looking volume while enhancing the texture and colour of the lips.

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Benefits of Restylane Kesse

  • Luscious, plumped lips

  • Soft, natural-looking results

  • Smooths lip lines and wrinkles

  • Enhances the colour of your lips

  • Allows for flexible lip movements

  • More defined, volumized, and youthful lips

  • Longer-lasting results as compared to other lip fillers

  • Immediate results with zero downtime

What to Expect

Step 1

All Restylane® Kysse fillers come with lidocaine, an anesthetic, to ensure that your treatment is relaxing and entirely comfortable. Initially, a topical anesthetic will be applied on the injection site to numb the area.

Step 2

Our aesthetic doctor will begin the procedure with the first injection using an ultra-fine needle, before taking a pause to allow the lidocaine in Restylane® Kysse to further numb the lip area.

Step 3

The procedure then continues until the treated area shows the desired results. Thereafter, the injected area will be massaged to ensure that the filler gel is distributed evenly across the lips for natural results.

Are there any before and after photos of Restylane® Kysse results?

As dictated by Ministry of Health, we are not allowed to publish ‘before’ and ‘after’ images of aesthetic treatments. If you are interested in seeing the full before-and-after results please provide us with your name and email below, and we will send the images to your email address.

Restylane Kysse Frequently Asked Questions
Am I an ideal candidate for Restylane® Kysse Lip Fillers?

Patients should not use Kysse lip filler if they:

  • Have a history of severe allergic reactions.

  • Have had a previous allergic reaction to hyaluronic acid fillers.

  • Are allergic to anesthetics, like lidocaine.

While both of these are hyaluronic acid lip fillers, they have slightly different formulas. Restylane® Kysse adds volume and enhances your existing lip shape and symmetry to create smooth, natural-looking lips. It can also treat smoker’s lines, or commonly known as wrinkles around the mouth.

Juvederm, on the other hand, is a great option for patients who are looking for a more voluminous look. When deciding on which lip filler, it depends on the look you want to achieve.

Due to the different formulations, Restylane® Kysse has a unique structure that lasts longer than other fillers. Most dermal lip fillers last around 9 months, however you can expect results lasting up to 12 months with Restylane® Kysse.

The discomfort experienced during the treatment varies from person to person and depends on factors such as:

  • Sensitivity of the patient

  • Pain tolerance of the patient

  • Anxiety level of the patient

Restylane® Kysse comes with anesthetic inside the gel already, hence discomfort is at its minimum.

All lip fillers have some mild side effects. You may experience some slight swelling and bruising on the injected area, but these should go away within 7 days.

  • As with other lip fillers treatment, a cold compress may be applied to the injected area to reduce swelling.

  • Avoid touching the injected area for at least 6 hours so that you do not accidentally injure your skin while the area is numb. Thereafter, the treatment area can be gently washed with soap and water.

  • Minimise strenuous exercise and exposure to excess heat, sun, or UV rays for the first 24 hours. Exposure to these may cause temporary redness, swelling, or itching at the treated area.

Full aftercare instructions will also be provided after the treatment.

Got more questions? Contact our clinic for more information or schedule an appointment with our doctor

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Acne

A commonly overlooked yet physically and psychologically scarring problem, acne is a long-drawn problem that commences at puberty and can drag on well into one’s 20s to 30s. Adult-onset acne is also common, commencing in one’s 20s to 30s and dragging on well beyond that. Caused mainly by accumulation of dead skin, bacterial infection and uncontrolled inflammation, acne is a rather well understood medical condition. Hormonal influences, genetic factors, and even proposed dietary influences are known to be the underlying drivers of acne in some too. Early intervention is the best solution – less acne translates to less scarring, saving you precious time and finances required in attempting to resurface those pesky scars later on.

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Acne Treatments

Chemical Peels

Chemical peels consist of mild acids that, when applied to skin, promote controlled exfoliation of skin as well as inactivation of the sebaceous units responsible for breakouts.

Used as a complimentary form of treatment to existing topical therapy, chemical peels can quickly and effectively control most forms of acne.

3-5 sessions are typically required at 2 weekly intervals to bring acne under control, with subsequent sessions done every 4-6 weeks for maintenance.

Find out more about Chemical Peels

Carbon Peel

Using a specialised laser and a black carbon-based ink on the face, sebaceous glands can be targeted, bacteria killed, and mild exfoliation performed.

Sessions done at 2-4 weekly intervals can help keep acne bay while also helping to lighten any post-inflammatory pigmentation left by the acne and even reduce pore size.

 Find out more about Chemical Peels

AGNES

For the larger, stubborn and recurrent acne, the use of a highly selective probe to deliver high radio-frequency energy into the sebaceous unit effectively and permanently inactivates the gland.

This more permanent solution to acne allows for effective management of recurrent acne without having to resort to oral medication such as oral isotretinoin.

Read more about AGNES acne treatment

Medical Facials for Acne Treatment

Gentle Medical Facial 

Perfect for unclogging pores and reducing P. acne presence in the skin, our gentle medical facial includes a session of microdermabrasion, a light chemical peel and a session with the Omnilux blue LED light  – a perfect combination for comedonal acne. 

Read more about Omnilux blue LED light

Sciton Blue BBL

Harnessing the power of intense blue light, the Sciton Blue BBL therapy eliminates one of the contributing factors of acne – the bacteria, P. Acne.

Stronger than LED light, BBL effectively reduces acne while calming the state of the skin as a whole. 

Read more about Sciton Blue BBL

Optimised Acne Treatment Programmes

Acne elimination programme

Combining the benefits of lasers and acids, this customised programmes aims at eliminating existing acne, preventing further acne formation and erasing the post-inflammatory hyperpigmentation formed by acne.  Skin is also renewed, texture improved and a fresh glow attained. With minimal downtime and side effects, this combination therapy is built to reign in those outbreaks.

Treatments for Freckles and Pigmentation

At The Aesthetic Studio Clinic & Surgery, we offer a variety of options for treating pigmentary problems, eliminating brown spots and uneven pigmentation. These treatments also provide additional benefits of rejuvenating the skin, improving texture and appearance, softening wrinkles, tightening the skin, removing redness and broken blood vessels.

Treatment for Freckles and Pigmentation with Topical Treatments and Creams
Topical treatments are critical to help fade brown discolouration and prevent new areas from appearing. We use established and well studied ingredients in our skincare products, such as retinoids (prescription strength vitamin A) and retinol, hydroquinones (prescription bleach at varying strengths), kojic acid, licorice, various alpha, beta, and poly hydroxy acids, exfoliants, and melanocyte stabilising products. The Aesthetic Studio carries distinguished dermatologic product lines such as Obagi, SkinCeuticals, PCA Skin, La Roche Posay, and other products only available to clinics.

Treatment for Freckles and Pigmentation with Chemical peels
We provide superficial, medium depth and deeper peels – tailored to our patients needs, pigmentation type and recovery time requirements. Even gentle light peels help fade freckles, sun spots, age spots, and other excess pigmentation to reveal clearer, younger-looking skin.

Treatment for Freckles and Pigmentation with Cosmelan® Depigmentation masque
Cosmelan® Depigmentation masque is a painless, single session, clinic applied treatment that particularly suitable for stubborn and dense pigmentation. Cosmelan®’s synergistic ingredients effect quick, effective blending and elimination of undesirable pigment. Cosmelan® is “sun-friendly”, and works well even on darker toned Asian and Latin skin. Cosmelan® will also produce a slight initial “peel” which helps refinish the skin surface while dramatically diminishing hyperpigmentation. This is followed by a specialised home skin care program to enhance, maintain and protect the new skin.

Treatment for Freckles and Pigmentation with Spectra Laser Toning
Spectra Laser Toning is an advanced treatment protocol that provides a gentle, safe, and effective treatment for stubborn blotchy hormonal pigmentation known as melasma. Spectra treatments also help with generalised pigmentation issues, redness, pore size, unwanted hair, acne, rosacea, and gently tightens and refreshes the skin. It is a favourite as there is no downtime or healing time.

Treatment for Freckles and Pigmentation with Intense Pulsed Light (IPL) – Sciton BBL
BBL/IPL treatments are the treatment of choice for reversing the signs of sun-damaged skin. It will gently reduce excess pigmentation on sun exposed areas of the body including the face, neck, chest, hands, and arms. In addition to treating brown spots, this light source treats redness, broken blood vessels, shrinks pore size, tightens skin, and can help with acne and rosacea. Maximum benefits are achieved with a series of 2 to 3 treatments.

Treatment for Freckles and Pigmentation with Fractional CO2 Laser Skin Resurfacing
Fractional Carbon Dioxide (CO2) laser skin resurfacing treatments even out skin colouring by removing the dull, damaged, outer layer of skin; while minimising downtime. In addition to treating pigmentation, these laser treatments will also improve skin texture, redness, pore size, and wrinkles, repairing sun damaged or acne-scarred skin, and treat pre-cancerous skin lesions.

At The Aesthetic Studio Clinic & Surgery, we are dedicated to enhancing the health and appearance of your skin through innovation and clinical excellence. For a comprehensive facial assessment, call +65 6737 1100 or click here for an appointment.

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Tattoo Removal
Tattoos, while easily placed, are much more complicated to erase. Newer methods of treatment are more reliable, and total time required for tattoo removal can be shortened to less than a year.

Tattoos, while easily placed, are much more complicated to erase. Existing therapies involve the use of nano-second Q-switched lasers, but treatments prove difficult with many requiring 2-3 years of repeated visits at 2-3 monthly intervals. Newer methods of treatment involve the use of newly developed pico-second lasers. These lasers, firing many times faster than conventional Q switched lasers, fracture pigments more effectively. In effect, treatments are more reliable, and total time required for tattoo removal can be shortened to less than a year.

Here at The Aesthetic Studio, we employ the use of the Lutronic Picoplus Pico-second laser for optimal tattoo removal; with 4 wavelengths of light at your disposal, removal of tattoos of varying colour and complexity just got easier.

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Tattoo Removal Treatment
Tattoo Removal

With a high energy output, a wide range of precisely controllable fluence output and four wavelengths of light for increased versatility, the Picoplus Pico-second laser is optimised for tattoo removal and pigment management. 

Depending on tattoo complexity, 5-10 sessions may be required at monthly intervals for optimal clearance.

Combination with ablative lasers may be advised to reduce post-laser blistering commonly associated with tattoo removal.

Read more about Lutronic Picoplus Laser

Read more about Tattoo Removal Treatments

Frequently Asked Questions